Pdxdc1 Gene Summary [Rat]
Predicted to enable carboxy-lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in carboxylic acid metabolic process. Predicted to be located in Golgi apparatus. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to several human genes including PDXDC1 (pyridoxal dependent decarboxylase domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pdxdc1 |
| Official Name | pyridoxal-dependent decarboxylase domain containing 1 [Source:RGD Symbol;Acc:1562597] |
| Ensembl ID | ENSRNOG00000002407 |
| Bio databases IDs | |
| Aliases | pyridoxal-dependent decarboxylase domain containing 1 |
| Synonyms | 2210010A19Rik, AA415817, Kiaa0251-hp, LOC108348184, LP8165, pyridoxal-dependent decarboxylase domain containing 1, RGD1562597 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- non-insulin-dependent diabetes mellitus
- metabolic syndrome X
- chromophobe renal cell carcinoma
- chromophobe renal cancer
- colorectal cancer
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pdxdc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carboxylic acid metabolic process
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- pyridoxal phosphate binding
- cadherin binding
- carboxy-lyase activity