Htr5b Gene Summary [Rat]
Enables G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; adenylate cyclase-inhibiting serotonin receptor signaling pathway; and chemical synaptic transmission. Predicted to be located in synapse. Predicted to be active in dendrite and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Htr5b |
| Official Name | 5-hydroxytryptamine (serotonin) receptor 5B [Source:RGD Symbol;Acc:62388] |
| Ensembl ID | ENSRNOG00000002549 |
| Bio databases IDs | |
| Aliases | 5-hydroxytryptamine (serotonin) receptor 5B |
| Synonyms | 5-Ht5b, 5-hydroxytryptamine (serotonin) receptor 5B, REC17 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Htr5b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- 5-HT1 receptor
- serotonin receptor
- G-protein-coupled receptor binding
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Htr5b gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane