Blzf1 Gene Summary [Rat]

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in Golgi organization and Golgi to plasma membrane protein transport. Located in Golgi membrane. Orthologous to human BLZF1 (basic leucine zipper nuclear factor 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Blzf1
Official Name
basic leucine zipper nuclear factor 1 [Source:RGD Symbol;Acc:1562452]
Ensembl ID
ENSRNOG00000002884
Bio databases IDs NCBI: 498266 Ensembl: ENSRNOG00000002884
Aliases basic leucine zipper nuclear factor 1
Synonyms 1700030G05RIK, basic leucine zipper nuclear factor 1, BLZF1L, GOLGIN-45, JEM-1, JEM-1s
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Blzf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin protein ligase binding
  • transcription regulator
  • enzyme binding
  • protein binding
  • DASH complex subunit Hsk3 like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • lipopolysaccharide
  • tretinoin
  • dexamethasone
  • garcinol
  • TNKS/TNKS2
  • peripheral blood monocytes
  • alitretinoin
  • IGF1R
  • WNT3A
  • XBP1
role in cell
  • morphology
  • organization
  • stacking in
  • stacking

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi-enriched fraction
  • Nucleus
  • Golgi Apparatus
  • Golgi membrane
  • nucleoplasm
  • detergent-soluble fraction

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Blzf1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • Golgi organization
  • Golgi to plasma membrane protein transport

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cis-Golgi network
  • cytoplasm
  • Golgi apparatus
  • Golgi membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • ubiquitin protein ligase binding
  • protein binding
  • enzyme binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.