Gprc5c Gene Summary [Rat]

Predicted to enable protein kinase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in centriolar satellite and cilium. Predicted to be part of receptor complex. Predicted to be active in extracellular exosome; intracellular membrane-bounded organelle; and plasma membrane. Orthologous to human GPRC5C (G protein-coupled receptor class C group 5 member C). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Gprc5c
Official Name
G protein-coupled receptor, class C, group 5, member C [Source:RGD Symbol;Acc:1311408]
Ensembl ID
ENSRNOG00000003144
Bio databases IDs NCBI: 287805 Ensembl: ENSRNOG00000003144
Aliases G protein-coupled receptor, class C, group 5, member C
Synonyms 1110028I06Rik, 3200002M13Rik, G protein-coupled receptor class C group 5 member C, G protein-coupled receptor, class C, group 5, member C, G protein-coupled receptor, family C, group 5, member C, RAIG-3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gprc5c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane sweet-taste receptor of 3 GCPR
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gprc5c gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • carcinoma in situ
  • epithelial cancer in situ
  • Huntington disease
  • opioid dependence
regulated by
role in cell
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cilia
  • cellular membrane
  • centrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gprc5c gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic vesicle membrane
  • extracellular vesicular exosome
  • intracellular membrane-bounded organelle
  • vesicle
  • receptor complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein kinase activator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.