Caskin1 Gene Summary [Rat]

Enables protein domain specific binding activity. Involved in signal transduction. Located in cytoplasm. Orthologous to human CASKIN1 (CASK interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Caskin1
Official Name
CASK interacting protein 1 [Source:RGD Symbol;Acc:620191]
Ensembl ID
ENSRNOG00000003195
Bio databases IDs NCBI: 140722 Ensembl: ENSRNOG00000003195
Aliases CASK interacting protein 1
Synonyms 3300002N10RIK, ANKS5A, C130061I24, C630036E02RIK, CASK interacting protein 1, mKIAA1306
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Caskin1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • Ankyrin repeats (many copies)
  • Caskin1 CASK-interaction domain
  • C-terminal region of Caskin
  • SAM (Sterile alpha motif )
  • Ankyrin repeats (3 copies)
  • protein domain specific binding
  • protein binding
  • identical protein binding
  • Ankyrin repeat
  • Src Homology 3 domain superfamily
  • Sterile alpha motif
  • Proline rich region of Caskin proteins
  • SAM domain (Sterile alpha motif)
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hyperalgesia
  • gait disturbance
regulated by
  • N2A cells
  • mir-21 (includes others)
role in cell
  • long-term potentiation
  • replication in
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • glutaminergic synapse
  • Cytoplasm
  • postsynaptic region
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Caskin1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.