Caskin1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity and protein domain specific binding activity. Involved in regulation of postsynaptic density assembly. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including adrenal gland; bladder; eye; intestine; and nervous system. Orthologous to human CASKIN1 (CASK interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Caskin1 |
| Official Name | CASK interacting protein 1 [Source:MGI Symbol;Acc:MGI:2442952] |
| Ensembl ID | ENSMUSG00000033597 |
| Bio databases IDs | |
| Aliases | CASK interacting protein 1 |
| Synonyms | 3300002N10RIK, ANKS5A, C130061I24, C630036E02RIK, CASK interacting protein 1, mKIAA1306 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Caskin1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- Caskin1 CASK-interaction domain
- C-terminal region of Caskin
- SAM (Sterile alpha motif )
- Ankyrin repeats (3 copies)
- protein domain specific binding
- protein binding
- identical protein binding
- Ankyrin repeat
- Src Homology 3 domain superfamily
- Sterile alpha motif
- Proline rich region of Caskin proteins
- SAM domain (Sterile alpha motif)
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- glutaminergic synapse
- Cytoplasm
- postsynaptic region
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Caskin1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding