Kcnc2

Enables delayed rectifier potassium channel activity; transmembrane transporter binding activity; and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Involved in several processes, including cellular response to nitric oxide; nervous system development; and protein complex oligomerization. Located in several cellular components, including axon; basolateral plasma membrane; and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Is active in GABA-ergic synapse and presynaptic membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 103. Orthologous to human KCNC2 (potassium voltage-gated channel subfamily C member 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kcnc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Kcnc2 gene, providing context for its role in the cell.