Syap1 Gene Summary [Rat]

Predicted to be involved in several processes, including TORC2 signaling; cellular response to epidermal growth factor stimulus; and cellular response to peptide hormone stimulus. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; perikaryon; and synaptic membrane. Predicted to be active in Golgi apparatus; nucleus; and synapse. Orthologous to human SYAP1 (synapse associated protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Syap1
Official Name
synapse associated protein 1 [Source:RGD Symbol;Acc:1303113]
Ensembl ID
ENSRNOG00000004304
Bio databases IDs NCBI: 302678 Ensembl: ENSRNOG00000004304
Aliases synapse associated protein 1
Synonyms 2010110O17Rik, BSTA, PRO3113, synapse associated protein 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Syap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • domain in transcription factors and synapse-associated proteins
  • BSD domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Klinefelter syndrome
regulated by
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • perinuclear region
  • Golgi Apparatus
  • cytosol
  • cytoplasmic face of plasma membrane
  • presynaptic membrane
  • postsynaptic membrane
  • nucleoplasm
  • growth cone
  • perikaryon
  • axons
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Syap1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular response to insulin stimulus
  • cellular response to platelet-derived growth factor stimulus
  • cellular response to epidermal growth factor stimulus
  • cell differentiation
  • positive regulation of fat cell differentiation
  • regulation of short-term neuronal synaptic plasticity
  • positive regulation of protein serine/threonine kinase activity

Cellular Component

Where in the cell the gene product is active
  • presynaptic membrane
  • Golgi apparatus
  • synapse
  • perikaryon
  • nucleoplasm
  • internal side of plasma membrane
  • growth cone
  • dendrite
  • nucleus
  • extracellular vesicular exosome
  • perinuclear region of cytoplasm
  • postsynaptic membrane
  • cytoplasm
  • cytosol
  • axon

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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