Syap1 Gene Summary [Mouse]
Involved in several processes, including TORC2 signaling; cellular response to epidermal growth factor stimulus; and positive regulation of fat cell differentiation. Located in several cellular components, including growth cone; perikaryon; and synaptic membrane. Is expressed in central nervous system; lower jaw incisor; and upper jaw incisor. Orthologous to human SYAP1 (synapse associated protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Syap1 |
| Official Name | synapse associated protein 1 [Source:MGI Symbol;Acc:MGI:1914293] |
| Ensembl ID | ENSMUSG00000031357 |
| Bio databases IDs | |
| Aliases | synapse associated protein 1 |
| Synonyms | 2010110O17Rik, BSTA, PRO3113, synapse associated protein 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Syap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- domain in transcription factors and synapse-associated proteins
- BSD domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- perinuclear region
- Golgi Apparatus
- cytosol
- cytoplasmic face of plasma membrane
- presynaptic membrane
- postsynaptic membrane
- nucleoplasm
- growth cone
- perikaryon
- axons
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Syap1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to insulin stimulus
- cellular response to platelet-derived growth factor stimulus
- cellular response to epidermal growth factor stimulus
- cell differentiation
- positive regulation of fat cell differentiation
- regulation of short-term neuronal synaptic plasticity
- positive regulation of protein serine/threonine kinase activity
Cellular Component
Where in the cell the gene product is active
- presynaptic membrane
- Golgi apparatus
- synapse
- perikaryon
- nucleoplasm
- internal side of plasma membrane
- growth cone
- dendrite
- nucleus
- extracellular vesicular exosome
- perinuclear region of cytoplasm
- postsynaptic membrane
- cytoplasm
- cytosol
- axon
Molecular Function
What the gene product does at the molecular level
- protein binding