Kcng3 Gene Summary [Rat]

Enables potassium channel regulator activity. Acts upstream of or within regulation of potassium ion transport. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Orthologous to human KCNG3 (potassium voltage-gated channel modifier subfamily G member 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Kcng3
Official Name
potassium voltage-gated channel modifier subfamily G member 3 [Source:RGD Symbol;Acc:628832]
Ensembl ID
ENSRNOG00000004535
Bio databases IDs NCBI: 171011 Ensembl: ENSRNOG00000004535
Aliases potassium voltage-gated channel modifier subfamily G member 3
Synonyms KV10.1, Kv10.1a, Kv10.1b, KV6.3, LOC105374537, potassium voltage-gated channel modifier subfamily G member 3, potassium voltage-gated channel, subfamily G, member 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kcng3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NAB domain
  • delayed rectifier potassium channel
  • Ion transport protein
  • Broad-Complex, Tramtrack and Bric a brac
  • BTB_POZ
  • potassium channel regulator
  • protein binding
  • ion channel

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • Parkinson disease
  • COVID-19
  • insomnia
  • clear cell sarcoma of the kidney
  • renal cancer
  • soft tissue sarcoma cancer
regulated by
regulates
  • K+

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Plasma Membrane
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Kcng3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transmembrane transport
  • protein homooligomerization
  • regulation of action potential

Cellular Component

Where in the cell the gene product is active
  • voltage-gated potassium channel complex
  • membrane
  • endoplasmic reticulum
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • delayed rectifier potassium channel activity

Gene-Specific Assays for Results You Can Trust

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