Erh Gene Summary [Rat]

Predicted to enable methyl-CpG binding activity. Predicted to be located in midbody and nucleus. Predicted to be part of methylosome. Orthologous to human ERH (ERH mRNA splicing and mitosis factor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Erh
Official Name
ERH, mRNA splicing and mitosis factor [Source:RGD Symbol;Acc:1595409]
Ensembl ID
ENSRNOG00000004883
Bio databases IDs NCBI: 681415 Ensembl: ENSRNOG00000004883
Aliases ERH, mRNA splicing and mitosis factor
Synonyms DROER, ERH mRNA splicing and mitosis factor, ERH, mRNA splicing and mitosis factor, LOC678886, Mer, PREI1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Erh often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • methyl-CpG binding
  • Enhancer of rudimentary
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • intrahepatic cholestasis of pregnancy
regulated by
  • beta-estradiol
  • EGF
  • Large T Antigen
  • HUWE1
  • E2F1
  • CD 437
  • NMS-873
regulates
  • pyrimidine nucleoside
  • SOCS3
  • nucleic acid component or derivative
role in cell
  • expression in
  • morphology
  • regulation in
  • regulation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • interchromatin granule cluster fractions
  • midbody

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Erh gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nucleobase-containing compound metabolic process
  • pyrimidine nucleoside metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • methylosome
  • midbody

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • methyl-CpG binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.