Dmac2l Gene Summary [Rat]

Predicted to enable metal ion binding activity. Predicted to be involved in ATP biosynthetic process and proton transmembrane transport. Predicted to be located in mitochondrion. Predicted to be part of proton-transporting ATP synthase complex. Predicted to be active in cytoplasm. Orthologous to human DMAC2L (distal membrane arm assembly component 2 like). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Dmac2l
Official Name
distal membrane arm assembly complex 2 like [Source:RGD Symbol;Acc:1359208]
Ensembl ID
ENSRNOG00000004893
Bio databases IDs NCBI: 362749 Ensembl: ENSRNOG00000004893
Aliases distal membrane arm assembly complex 2 like
Synonyms 1110015E18RIK, ATP5S, ATPW, distal membrane arm assembly component 2 like, FB, HSU79253
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dmac2l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • adenosine-tetraphosphatase
  • protein binding
  • transporter

Pathways

Biological processes and signaling networks where the Dmac2l gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hereditary disorder
  • L-2 hydroxyglutaric aciduria
regulated by
regulates
  • ATP synthase
  • N-alpha-acetyl-Gly-Lys-methyl ester
role in cell
  • cytolysis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Dmac2l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ATP biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • proton-transporting ATP synthase complex, coupling factor F(o)
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • hydrogen ion transmembrane transporter activity
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.