Tmem18 Gene Summary [Rat]

Predicted to enable DNA binding activity. Involved in cell migration. Predicted to be located in cytoplasm. Predicted to be active in nuclear membrane. Orthologous to human TMEM18 (transmembrane protein 18). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tmem18
Official Name
transmembrane protein 18 [Source:RGD Symbol;Acc:1359389]
Ensembl ID
ENSRNOG00000005144
Bio databases IDs NCBI: 362722 Ensembl: ENSRNOG00000005144
Aliases transmembrane protein 18
Synonyms BC024093, lncND, transmembrane protein 18
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Transmembrane protein 18

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • weight gain
regulated by
role in cell
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem18 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • energy homeostasis
  • cell migration
  • eating behavior

Cellular Component

Where in the cell the gene product is active
  • nuclear membrane
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • DNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.