Chst5

Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and keratan sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process; keratan sulfate proteoglycan biosynthetic process; and sulfur compound metabolic process. Predicted to be located in Golgi membrane. Predicted to be active in trans-Golgi network. Human ortholog(s) of this gene implicated in macular corneal dystrophy. Orthologous to several human genes including CHST6 (carbohydrate sulfotransferase 6). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Chst5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Chst5 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Chst5 gene, providing context for its role in the cell.