Nxph3 Gene Summary [Rat]

Predicted to enable signaling receptor binding activity. Predicted to be located in extracellular region. Orthologous to human NXPH3 (neurexophilin 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nxph3
Official Name
neurexophilin 3 [Source:RGD Symbol;Acc:620693]
Ensembl ID
ENSRNOG00000005185
Bio databases IDs NCBI: 59315 Ensembl: ENSRNOG00000005185
Aliases neurexophilin 3
Synonyms neurexophilin 3, NPH3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nxph3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Neurexophilin
  • receptor binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Cornelia de Lange syndrome
regulated by
  • beta-estradiol
  • MECP2
  • TCF20
  • estradiol-17beta-benzoate
  • SORL1
  • molybdenum disulfide
  • 10E,12Z-octadecadienoic acid
  • RAD21

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nxph3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuropeptide signaling pathway

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • receptor binding