Cpa6 Gene Summary [Rat]
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpa6 |
| Official Name | carboxypeptidase A6 [Source:RGD Symbol;Acc:1311764] |
| Ensembl ID | ENSRNOG00000005655 |
| Bio databases IDs | |
| Aliases | carboxypeptidase A6 |
| Synonyms | 9030616D13, 9030616D13Rik, carboxypeptidase A6, CPAH, ETL5, FEB11 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpa6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc carboxypeptidase
- Zn_pept domain
- peptidase
- M14 family of metallocarboxypeptidases and related proteins
- Carboxypeptidase activation peptide
Pathways
Biological processes and signaling networks where the Cpa6 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- benign rolandic epilepsy
- tuberculosis
- familial temporal lobe epilepsy type 5
- familial febrile seizures type 11
- gastroesophageal reflux
- epilepsy
- cerebral amyloid angiopathy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cpa6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- metallocarboxypeptidase activity