Art4 Gene Summary [Rat]

Predicted to enable NAD+ poly-ADP-ribosyltransferase activity. Orthologous to human ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Art4
Official Name
ADP-ribosyltransferase 4 (Dombrock blood group) [Source:RGD Symbol;Acc:1306456]
Ensembl ID
ENSRNOG00000005670
Bio databases IDs NCBI: 312806 Ensembl: ENSRNOG00000005670
Aliases ADP-ribosyltransferase 4 (Dombrock blood group)
Synonyms 4432404K01Rik, ADP-ribosyltransferase 4, ADP-ribosyltransferase 4 (inactive) (Dombrock blood group), ARTC4, ATR4, CD297, DO, DO/ART4, DOK1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Art4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • VIP2
  • NAD(P)-arginine ADP-ribosyltransferase
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • TMPRSS2-ERG
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cell surface
  • Extracellular Space
  • cellular membrane
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Art4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • arginine metabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • nucleotidyltransferase activity
  • NAD+ ADP-ribosyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.