Art4 Gene Summary [Mouse]
Predicted to enable NAD+ poly-ADP-ribosyltransferase activity. Predicted to be located in plasma membrane and side of membrane. Is expressed in several structures, including cardiovascular system; genitourinary system; integumental system; liver; and sensory organ. Orthologous to human ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Art4 |
| Official Name | ADP-ribosyltransferase 4 [Source:MGI Symbol;Acc:MGI:1202710] |
| Ensembl ID | ENSMUSG00000030217 |
| Bio databases IDs | |
| Aliases | ADP-ribosyltransferase 4 |
| Synonyms | 4432404K01Rik, ADP-ribosyltransferase 4, ADP-ribosyltransferase 4 (inactive) (Dombrock blood group), ARTC4, ATR4, CD297, DO, DO/ART4, DOK1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Art4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- VIP2
- NAD(P)-arginine ADP-ribosyltransferase
- enzyme
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cell surface
- Extracellular Space
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Art4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- arginine metabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- nucleotidyltransferase activity
- NAD+ ADP-ribosyltransferase activity