Asb15 Gene Summary [Rat]

Predicted to be involved in intracellular signal transduction and protein ubiquitination. Orthologous to human ASB15 (ankyrin repeat and SOCS box containing 15). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Asb15
Official Name
ankyrin repeat and SOCS box containing 15 [Source:RGD Symbol;Acc:727860]
Ensembl ID
ENSRNOG00000006365
Bio databases IDs NCBI: 500050 Ensembl: ENSRNOG00000006365
Aliases ankyrin repeat and SOCS box containing 15
Synonyms 4930400E23Rik, ankyrin repeat and SOCS box-containing 15
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Asb15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SOCS box
  • transcription regulator
  • Ankyrin repeats (many copies)
  • Ankyrin repeats (3 copies)
  • SOCS
  • protein binding
  • Ankyrin repeat
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • acute myeloid leukemia
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
  • heart failure
role in cell
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Asb15 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • Golgi to lysosome transport
  • retrograde transport, endosome to Golgi
  • intracellular signal transduction
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • endosome membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • small GTPase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.