Krt75 Gene Summary [Rat]
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in intermediate filament. Predicted to be active in cornified envelope and keratin filament. Orthologous to human KRT75 (keratin 75). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt75 |
| Official Name | keratin 75 [Source:RGD Symbol;Acc:1359576] |
| Ensembl ID | ENSRNOG00000043203 |
| Bio databases IDs | |
| Aliases | keratin 75 |
| Synonyms | CK-75, hK6hf, K6HF, K75, KB18, keratin 75, PFB |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Krt75 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR/MLP1/MLP2-like protein
- Myosin-like coiled-coil protein
- protein binding
- Intermediate filament protein
- Keratin type II head
- structural molecule
Pathways
Biological processes and signaling networks where the Krt75 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
- intermediate filaments
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Krt75 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- keratinization
- intermediate filament organization
- hemopoietic progenitor cell differentiation
Cellular Component
Where in the cell the gene product is active
- cornified envelope
- keratin filament
- extracellular vesicular exosome
- cytosol
- intermediate filament
Molecular Function
What the gene product does at the molecular level
- structural constituent of epidermis
- protein binding
- structural molecule activity