Asb15 Gene Summary [Mouse]
Predicted to be involved in negative regulation of canonical Wnt signaling pathway; positive regulation of JNK cascade; and protein targeting to chloroplast. Predicted to be active in nucleus. Is expressed in genitourinary system; quadriceps femoris muscle; thoracic segment skeleton; and tongue. Orthologous to human ASB15 (ankyrin repeat and SOCS box containing 15). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Asb15 |
| Official Name | ankyrin repeat and SOCS box-containing 15 [Source:MGI Symbol;Acc:MGI:1926160] |
| Ensembl ID | ENSMUSG00000029685 |
| Bio databases IDs | |
| Aliases | ankyrin repeat and SOCS box-containing 15 |
| Synonyms | 4930400E23Rik, ankyrin repeat and SOCS box-containing 15 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Asb15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SOCS box
- transcription regulator
- Ankyrin repeats (many copies)
- Ankyrin repeats (3 copies)
- SOCS
- protein binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Asb15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Golgi to lysosome transport
- retrograde transport, endosome to Golgi
- intracellular signal transduction
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosol
- endosome membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- small GTPase binding