Bms1 Gene Summary [Rat]
Predicted to enable GTP binding activity; GTPase activity; and U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of small-subunit processome. Human ortholog(s) of this gene implicated in nonsyndromic aplasia cutis congenita. Orthologous to human BMS1 (BMS1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bms1 |
| Official Name | BMS1 ribosome biogenesis factor [Source:RGD Symbol;Acc:1308043] |
| Ensembl ID | ENSRNOG00000006576 |
| Bio databases IDs | |
| Aliases | BMS1 ribosome biogenesis factor |
| Synonyms | ACC, AU020092, AU043373, BB007109, BMS1L, BMS1 ribosome biogenesis factor, BMS1, ribosome biogenesis factor, KIAA0187, mKIAA0187 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Bms1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
- 50S ribosome-binding GTPase
- protein binding
- AARP2CN (NUC121) domain
- Elongation factor Tu GTP binding domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- Cytoplasm
- chromosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Bms1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- ribosomal small subunit biogenesis
- endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- chromosome
- nucleolus
- 90S preribosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- GTP binding
- ATP binding
- RNA binding
- GTPase activity
- U3 snoRNA binding