Reg3g Gene Summary [Rat]
Predicted to enable several functions, including hormone activity; oligosaccharide binding activity; and peptidoglycan binding activity. Predicted to be involved in several processes, including negative regulation of keratinocyte differentiation; regulation of response to wounding; and response to bacterium. Predicted to act upstream of or within response to bacterium. Predicted to be located in secretory granule. Predicted to be active in extracellular space. Orthologous to human REG3G (regenerating family member 3 gamma). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Reg3g |
| Official Name | regenerating family member 3 gamma [Source:RGD Symbol;Acc:3256] |
| Ensembl ID | ENSRNOG00000006579 |
| Bio databases IDs | |
| Aliases | regenerating family member 3 gamma |
| Synonyms | PAP3, PAPIII, REG-3-gamma, REG-3-γ, regenerating family member 3 gamma, regenerating family member 3 γ, Regenerating islet derived 3 gamma, Regenerating islet derived 3 γ, REG III gamma, REG III γ |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Reg3g often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- peptidoglycan binding
- hormone
- carbohydrate binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- dextran sodium sulfate-induced colitis
- infection by Citrobacter rodentium
role in cell
- proliferation
- number
- differentiation
- recruitment
- killing
- clearance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- secretory granules