Slc38a4 Gene Summary [Rat]

Enables neutral L-amino acid:sodium symporter activity. Involved in neutral amino acid transport. Predicted to be located in microvillus membrane. Predicted to be active in plasma membrane. Orthologous to human SLC38A4 (solute carrier family 38 member 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc38a4
Official Name
solute carrier family 38, member 4 [Source:RGD Symbol;Acc:621836]
Ensembl ID
ENSRNOG00000006653
Bio databases IDs NCBI: 170573 Ensembl: ENSRNOG00000006653
Aliases solute carrier family 38, member 4
Synonyms 1110012E16Rik, 1700012A18Rik, ATA3, mATA3, mNAT3, NAT3, PAAT, SNAT4, solute carrier family 38 member 4, solute carrier family 38, member 4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc38a4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • neutral amino acid:sodium symporter
  • organic cation transporter
  • alanine:sodium symporter
  • L-amino acid transporter
  • sodium:amino acid transporter
  • protein binding
  • basic amino acid transporter
  • Solute carrier families 5 and 6-like; solute binding domain
  • amino acid transporter
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • liver cancer
  • hepatitis B virus-related hepatocellular carcinoma
regulated by
regulates
  • amino acids
  • L-alanine
  • neutral amino acid
  • L-arginine
  • ligands of SLC38A4
  • glutamine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • microvilli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc38a4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neutral amino acid transport
  • sodium ion transmembrane transport
  • amino acid transport
  • amino acid transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • microvillus membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • L-amino acid transmembrane transporter activity
  • protein binding
  • neutral amino acid:sodium symporter activity
  • sodium:amino acid symporter activity
  • amino acid transmembrane transporter activity
  • alanine:sodium symporter activity

Gene-Specific Assays for Results You Can Trust

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