Pgap4 Gene Summary [Rat]

Predicted to enable glycosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human PGAP4 (post-GPI attachment to proteins GalNAc transferase 4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Pgap4
Official Name
post-GPI attachment to proteins GalNAc transferase 4 [Source:RGD Symbol;Acc:1307218]
Ensembl ID
ENSRNOG00000006800
Bio databases IDs NCBI: 362518 Ensembl: ENSRNOG00000006800
Aliases post-GPI attachment to proteins GalNAc transferase 4
Synonyms 2810432L12Rik, 9330170P15Rik, C9orf125, MGC12992, post-GPI attachment to proteins GalNAc transferase 4, RGD1307218, TMEM246
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pgap4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • enzyme
  • glycosyltransferase
  • Post-GPI attachment to proteins factor 4 and similar proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cervical cancer
  • senile cataract
  • thyroiditis
regulated by
  • ZIC2
  • H1-1
  • H1-6
  • Dengue virus 2 Thailand/NGS-C/1944
  • quercetin
regulates
  • ALP

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pgap4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • GPI anchor biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • transferase activity, transferring glycosyl groups

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.