Pgap4 Gene Summary [Mouse]
Predicted to enable glycosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in Golgi membrane. Is expressed in ganglia; nucleus pulposus; and thymus primordium. Orthologous to human PGAP4 (post-GPI attachment to proteins GalNAc transferase 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pgap4 |
| Official Name | post-GPI attachment to proteins GalNAc transferase 4 [Source:MGI Symbol;Acc:MGI:1914313] |
| Ensembl ID | ENSMUSG00000039611 |
| Bio databases IDs | |
| Aliases | post-GPI attachment to proteins GalNAc transferase 4 |
| Synonyms | 2810432L12Rik, 9330170P15Rik, C9orf125, MGC12992, post-GPI attachment to proteins GalNAc transferase 4, RGD1307218, TMEM246 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pgap4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme
- glycosyltransferase
- Post-GPI attachment to proteins factor 4 and similar proteins
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pgap4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- GPI anchor biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- transferase activity, transferring glycosyl groups