Ergic3 Gene Summary [Rat]
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; positive regulation of intracellular protein transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment membrane. Predicted to be part of retrograde transporter complex, Golgi to ER. Predicted to be active in COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum membrane. Orthologous to human ERGIC3 (ERGIC and golgi 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ergic3 |
| Official Name | ERGIC and golgi 3 [Source:RGD Symbol;Acc:1308144] |
| Ensembl ID | ENSRNOG00000031085 |
| Bio databases IDs | |
| Aliases | ERGIC and golgi 3 |
| Synonyms | 2310015B14Rik, AV318804, C20orf47, C2orf47, CGI-54, D2Ucla1, dJ477O4.2, ERGIC, ERGIC and golgi 3, Erv46, NY-BR-84, PRO0989, SDBCAG84 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ergic3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
- Endoplasmic reticulum vesicle transporter
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- ER-to-Golgi intermediate compartment
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ergic3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of intracellular protein transport
- ER to Golgi vesicle-mediated transport
- retrograde vesicle-mediated transport, Golgi to ER
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- Golgi membrane
- endoplasmic reticulum
- ER to Golgi transport vesicle
- endoplasmic reticulum-Golgi intermediate compartment membrane
Molecular Function
What the gene product does at the molecular level
- protein binding