Zcchc3 Gene Summary [Rat]

Enables double-stranded DNA binding activity. Involved in several processes, including cellular response to exogenous dsRNA; detection of virus; and positive regulation of RIG-I signaling pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Zcchc3
Official Name
zinc finger CCHC-type containing 3 [Source:RGD Symbol;Acc:1585203]
Ensembl ID
ENSRNOG00000007520
Bio databases IDs NCBI: 690005 Ensembl: ENSRNOG00000007520
Aliases zinc finger CCHC-type containing 3
Synonyms 2810406K24Rik, C20orf99, LOC682483, zinc finger, CCHC domain containing 3, zinc finger CCHC-type containing 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zcchc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • double-stranded DNA binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulates
  • IFN

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zcchc3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular response to exogenous dsRNA
  • activation of innate immune response
  • innate immune response
  • positive regulation of type I interferon production
  • defense response to virus
  • positive regulation of RIG-I signaling pathway
  • detection of virus

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • RNA binding
  • double-stranded DNA binding

Gene-Specific Assays for Results You Can Trust

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