Zcchc3 Gene Summary [Mouse]
Predicted to enable double-stranded DNA binding activity. Involved in several processes, including cellular response to exogenous dsRNA; defense response to virus; and positive regulation of type I interferon production. Predicted to be active in cytoplasm. Is expressed in Meckel's cartilage; medulla oblongata basal plate mantle layer; skeleton; and ventral grey horn. Orthologous to human ZCCHC3 (zinc finger CCHC-type containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zcchc3 |
| Official Name | zinc finger, CCHC domain containing 3 [Source:MGI Symbol;Acc:MGI:1915167] |
| Ensembl ID | ENSMUSG00000074682 |
| Bio databases IDs | |
| Aliases | zinc finger, CCHC domain containing 3 |
| Synonyms | 2810406K24Rik, C20orf99, LOC682483, zinc finger, CCHC domain containing 3, zinc finger CCHC-type containing 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zcchc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- double-stranded DNA binding
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zcchc3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to exogenous dsRNA
- activation of innate immune response
- innate immune response
- positive regulation of type I interferon production
- defense response to virus
- positive regulation of RIG-I signaling pathway
- detection of virus
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- RNA binding
- double-stranded DNA binding