ZCCHC3 Gene Summary [Human]
Enables double-stranded DNA binding activity. Involved in several processes, including cellular response to exogenous dsRNA; detection of virus; and positive regulation of RIG-I signaling pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZCCHC3 |
| Official Name | zinc finger CCHC-type containing 3 [Source:HGNC Symbol;Acc:HGNC:16230] |
| Ensembl ID | ENSG00000247315 |
| Bio databases IDs | |
| Aliases | zinc finger CCHC-type containing 3 |
| Synonyms | 2810406K24Rik, C20orf99, LOC682483, zinc finger, CCHC domain containing 3, zinc finger CCHC-type containing 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZCCHC3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- double-stranded DNA binding
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZCCHC3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to exogenous dsRNA
- activation of innate immune response
- innate immune response
- positive regulation of type I interferon production
- defense response to virus
- positive regulation of RIG-I signaling pathway
- detection of virus
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- RNA binding
- double-stranded DNA binding