Cct6b Gene Summary [Rat]

Predicted to enable protein folding chaperone and unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytosol. Predicted to be part of chaperonin-containing T-complex. Orthologous to human CCT6B (chaperonin containing TCP1 subunit 6B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cct6b
Official Name
chaperonin containing TCP1 subunit 6B [Source:RGD Symbol;Acc:1359453]
Ensembl ID
ENSRNOG00000007523
Bio databases IDs NCBI: 363658 Ensembl: ENSRNOG00000007523
Aliases chaperonin containing TCP1 subunit 6B
Synonyms CCTZ-2, CCT-zeta-2, CCT-zeta-like, CCT-ζ-2, CCT-ζ-like, chaperonin containing TCP1 subunit 6B, RGD1561014, TCP-1-zeta-2, TCP-1-ζ-2, TSA303
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cct6b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • T-complex protein 1, beta subunit
  • T-complex protein 1, alpha subunit
  • T-complex protein 1, zeta subunit
  • thermosome, various subunits, archaeal
  • T-complex protein 1, eta subunit
  • T-complex protein 1, delta subunit
  • T-complex protein 1, gamma subunit
  • protein binding
  • chaperonin_like
  • TCP-1/cpn60 chaperonin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • mature B-cell neoplasia
  • brain cancer
  • Burkitt lymphoma
  • B-cell non-Hodgkin disease
regulated by
  • diphtheria toxin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cct6b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • chaperonin-containing T-complex
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding
  • protein binding involved in protein folding
  • unfolded protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.