Hnrnpm Gene Summary [Rat]
Enables calcium-dependent protein binding activity and protein antigen binding activity. Involved in several processes, including cellular response to carcinoembryonic antigen; cellular response to lipopolysaccharide; and positive regulation of protein localization. Located in cell surface. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human HNRNPM (heterogeneous nuclear ribonucleoprotein M). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hnrnpm |
| Official Name | heterogeneous nuclear ribonucleoprotein M [Source:RGD Symbol;Acc:620369] |
| Ensembl ID | ENSRNOG00000007921 |
| Bio databases IDs | |
| Aliases | heterogeneous nuclear ribonucleoprotein M |
| Synonyms | 2610023M21Rik, CEAR, Heterogeneous nuclear ribonucleoprotein m, HNRNPM4, HNRPM, HNRPM4, HTGR1, mKIAA4193, NAGR1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hnrnpm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- calcium-dependent protein binding
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- HnRNP M nuclear localization signal
- antigen binding
- protein domain specific binding
- protein binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cardiovascular disorder
- coronary artery disease
- breast cancer
- metastasis
regulates
role in cell
- growth
- production in
- epithelial-mesenchymal transition
- alternative splicing by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- detergent resistant lipid raft fraction
- glutaminergic synapse
- catalytic step 2 spliceosome
- cell surface
- spliceosomes
- nuclear pores
- nucleoplasm
- nucleoli
- nuclear bodies
- nuclear rim
- interchromatin granule clusters
- nuclear envelope
- nuclear matrix
- synapse
- postsynaptic density
- detergent-soluble fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Hnrnpm gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- alternative nuclear mRNA splicing, via spliceosome
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- catalytic step 2 spliceosome
- paraspeckles
- membrane
- spliceosomal complex
- nuclear matrix
- synapse
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein domain specific binding
- RNA binding
- protein binding
- mRNA binding