Anxa13 Gene Summary [Rat]
Predicted to enable calcium ion binding activity and phospholipid binding activity. Predicted to be involved in negative regulation of Golgi to plasma membrane protein transport and positive regulation of Golgi to plasma membrane protein transport. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and exocytic vesicle. Predicted to be active in several cellular components, including nucleus; plasma membrane; and vesicle membrane. Orthologous to human ANXA13 (annexin A13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Anxa13 |
| Official Name | annexin A13 [Source:RGD Symbol;Acc:1307545] |
| Ensembl ID | ENSRNOG00000007980 |
| Bio databases IDs | |
| Aliases | annexin A13 |
| Synonyms | 1810034H17Rik, annexin A13, ANX13, ISA |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Anxa13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- binding protein
- calcium ion binding
- calcium-dependent phospholipid binding
- Annexin
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- alloxan-induced diabetic nephropathy
- otitis media
- plasma cell myeloma
- conductive hearing loss
- Eustachian tube disorder
- pelvic organ prolapse
- breast carcinoma
role in cell
- formation
- upregulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- golgi/trans-golgi network-rich vesicle fraction
- exocytic vesicle
- intracellular space
- apical compartment
- cellular membrane
- vesicles
- apical cytoplasm
- basolateral cytoplasm
- apical cell surfaces
- apical membrane
- basolateral membrane
- trans Golgi network
- nucleoplasm
- membrane rafts
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Anxa13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular space
- extracellular vesicular exosome
- cytoplasm
- vesicle membrane
- membrane
- cytoplasmic vesicle
- apical plasma membrane
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- phosphatidylserine binding
- calcium ion binding
- calcium-dependent phospholipid binding