Synpr Gene Summary [Rat]

Involved in modulation of chemical synaptic transmission. Is active in hippocampal mossy fiber to CA3 synapse and synaptic vesicle membrane. Orthologous to human SYNPR (synaptoporin). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Synpr
Official Name
synaptoporin [Source:RGD Symbol;Acc:708366]
Ensembl ID
ENSRNOG00000008203
Bio databases IDs NCBI: 66030 Ensembl: ENSRNOG00000008203
Aliases synaptoporin
Synonyms 1500003F20Rik, LOC66030, SPO, Synaptophysin2, synaptoporin
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Synpr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Membrane-associating domain
  • protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • Huntington disease
  • major depression
  • idiopathic scoliosis
  • gestational diabetes mellitus
  • chronic autoimmune hepatitis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • synaptic vesicle membrane
  • synaptic membrane
  • synaptic vesicles
  • neurites
  • synaptosomes
  • synapse
  • mossy fiber boutons
  • clathrin-coated vesicles
  • mossy fibers

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Synpr gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • synaptic vesicle membrane
  • neuron projection

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.