Pitpnm3 Gene Summary [Rat]
Predicted to enable calcium ion binding activity; phospholipase activity; and receptor tyrosine kinase binding activity. Predicted to be involved in phospholipid transport. Located in cell body and cell projection. Human ortholog(s) of this gene implicated in cone-rod dystrophy 5. Orthologous to human PITPNM3 (PITPNM family member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pitpnm3 |
| Official Name | PITPNM family member 3 [Source:RGD Symbol;Acc:1308200] |
| Ensembl ID | ENSRNOG00000008323 |
| Bio databases IDs | |
| Aliases | PITPNM family member 3 |
| Synonyms | A330068P14, A330068P14Rik, ACKR6, AI848332, CORD5, Gm880, NIR1, PITPNM family member 3, RDGBA3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pitpnm3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- receptor tyrosine kinase binding
- DDHD domain
- calcium ion binding
- phosphatidylinositol transporter
- enzyme
- protein binding
- acidic domain
- Haloacid Dehalogenase-like Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- cytosol
- photoreceptor inner segments
- cellular protrusions
- membrane processes
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pitpnm3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid transport
- phosphatidylinositol biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- cell body
- cytosol
- endomembrane system
- cell projection
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- lipid binding
- phosphatidylinositol transporter activity
- receptor tyrosine kinase binding
- phospholipase activity