Ubiad1 Gene Summary [Rat]
Predicted to enable antioxidant activity and prenyltransferase activity. Predicted to be involved in several processes, including endothelial cell development; ketone biosynthetic process; and phylloquinone metabolic process. Predicted to be located in cytoplasm; membrane; and nucleus. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Schnyder corneal dystrophy. Orthologous to human UBIAD1 (UbiA prenyltransferase domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ubiad1 |
| Official Name | UbiA prenyltransferase domain containing 1 [Source:RGD Symbol;Acc:1309588] |
| Ensembl ID | ENSRNOG00000009575 |
| Bio databases IDs | |
| Aliases | UbiA prenyltransferase domain containing 1 |
| Synonyms | 1200002M06Rik, RGD1309588, SCCD, TERE1, UbiA prenyltransferase domain containing 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ubiad1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- prenyltransferase
- enzyme
- antioxidant enzyme
- protein binding
- UbiA family of prenyltransferases (PTases)
- UbiA prenyltransferase family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Schnyder crystalline corneal dystrophy
- gastrulation failure
- senile lentigo
regulates
- HDL/cholesterol
- cholesterol
- vitamin K
- vitamin K2
- HMGCR
- vitamin
- vitamin K1
- ubiquinone
role in cell
- growth
- proliferation
- ploidy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ubiad1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate
- vitamin K biosynthetic process
- vitamin K metabolic process
- menaquinone biosynthetic process
- ubiquinone biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nucleus
- mitochondrial membrane
- cytoplasm
- membrane
- Golgi membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding
- antioxidant activity
- prenyltransferase activity
- 4-hydroxybenzoate decaprenyltransferase activity