Cplx4 Gene Summary [Rat]
Predicted to enable SNARE binding activity. Predicted to be involved in modulation of chemical synaptic transmission; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle exocytosis. Predicted to act upstream of or within regulation of neurotransmitter secretion. Predicted to be located in synapse. Predicted to be part of SNARE complex. Predicted to be active in terminal bouton. Orthologous to human CPLX4 (complexin 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cplx4 |
| Official Name | complexin 4 [Source:RGD Symbol;Acc:1307643] |
| Ensembl ID | ENSRNOG00000016928 |
| Bio databases IDs | |
| Aliases | complexin 4 |
| Synonyms | A930004D23Rik, complexin 4, CPX-IV, Gm957 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cplx4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNARE binding
- Synaphin protein
- Complexin_NTD
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cplx4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of neurotransmitter secretion
- synaptic vesicle exocytosis
- visual perception
Cellular Component
Where in the cell the gene product is active
- terminal button
- SNARE complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- SNARE binding