Nyx Gene Summary [Rat]

Predicted to act upstream of or within visual perception. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1A and night blindness. Orthologous to human NYX (nyctalopin). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Nyx
Official Name
nyctalopin [Source:RGD Symbol;Acc:1561300]
Ensembl ID
ENSRNOG00000009646
Bio databases IDs NCBI: 302516 Ensembl: ENSRNOG00000009646
Aliases nyctalopin
Synonyms CLNP, CLRP, CSNB1, CSNB1A, CSNB4, NBM1, nob, nyctalopin, RGD1561300
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nyx often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Leucine-rich repeats, outliers
  • Leucine-rich repeats, typical (most populated) subfamily
  • protein phosphatase 1 regulatory subunit 42
  • Leucine rich repeat
  • protein binding
  • Leucine rich repeat N-terminal domain
  • Leucine Rich repeats (2 copies)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • congenital stationary night blindness type 1
  • congenital stationary night blindness type 1A
  • retinal dystrophy
  • NYX-related retinopathy
  • congenital stationary night blindness
regulated by
  • dexamethasone
regulates
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nyx gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • visual perception

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular matrix

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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