Nyx Gene Summary [Mouse]
Acts upstream of or within visual perception. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Used to study congenital stationary night blindness 1A. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1A and night blindness. Orthologous to human NYX (nyctalopin). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nyx |
| Official Name | nyctalopin [Source:MGI Symbol;Acc:MGI:2448607] |
| Ensembl ID | ENSMUSG00000051228 |
| Bio databases IDs | |
| Aliases | nyctalopin |
| Synonyms | CLNP, CLRP, CSNB1, CSNB1A, CSNB4, NBM1, nob, nyctalopin, RGD1561300 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nyx often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine-rich repeats, outliers
- Leucine-rich repeats, typical (most populated) subfamily
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat
- protein binding
- Leucine rich repeat N-terminal domain
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nyx gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- visual perception
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular matrix
Molecular Function
What the gene product does at the molecular level
- protein binding