Tmem41b Gene Summary [Rat]
Predicted to enable phospholipid scramblase activity. Predicted to be involved in autophagosome assembly and intracellular lipid transport. Predicted to be located in mitochondria-associated endoplasmic reticulum membrane contact site. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human TMEM41B (transmembrane protein 41B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem41b |
| Official Name | transmembrane protein 41B [Source:RGD Symbol;Acc:1310870] |
| Ensembl ID | ENSRNOG00000010752 |
| Bio databases IDs | |
| Aliases | transmembrane protein 41B |
| Synonyms | 1500015G02Rik, 1500031M19Rik, D7Ertd70e, D7Ertd743e, KIAA0033, RGD1310870, transmembrane protein 41B |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem41b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid scramblase
- SNARE associated Golgi protein
- DedA
- protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum mitochondria contact site
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem41b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagic vacuole assembly
- nervous system development
- phospholipid scrambling
- intracellular lipid transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- ER-mitochondrion membrane contact site
Molecular Function
What the gene product does at the molecular level
- protein binding
- phospholipid scramblase activity