Tekt2 Gene Summary [Rat]

Predicted to be involved in cilium assembly and flagellated sperm motility. Predicted to act upstream of or within inner dynein arm assembly. Predicted to be located in axonemal microtubule and microtubule organizing center. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. Orthologous to human TEKT2 (tektin 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tekt2
Official Name
tektin 2 [Source:RGD Symbol;Acc:1311065]
Ensembl ID
ENSRNOG00000011033
Bio databases IDs NCBI: 298532 Ensembl: ENSRNOG00000011033
Aliases tektin 2
Synonyms h-tektin-t, TEKTB1, tektin 2, TEKTIN-T
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tekt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Tektin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • nonobstructive azoospermia
regulated by
  • lipopolysaccharide
  • ULK4
regulates
  • NPHS1
  • Axonemal Dynein Inner Arm
role in cell
  • expression in
  • motility
  • remodeling in
  • remodeling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • flagella
  • axonemes
  • microtubule organizing centers
  • sperm tail

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tekt2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm motility
  • cilium morphogenesis
  • cilium movement involved in cell motility
  • inner dynein arm assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • axonemal microtubule
  • microtubule cytoskeleton
  • motile cilium
  • microtubule organizing center

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.