Inmt Gene Summary [Rat]
Predicted to enable N-methyltransferase activity; amine N-methyltransferase activity; and thioether S-methyltransferase activity. Predicted to be involved in amine metabolic process and methylation. Predicted to be active in cytosol. Orthologous to human INMT (indolethylamine N-methyltransferase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Inmt |
| Official Name | indolethylamine N-methyltransferase [Source:RGD Symbol;Acc:1597087] |
| Ensembl ID | ENSRNOG00000011250 |
| Bio databases IDs | |
| Aliases | indolethylamine N-methyltransferase |
| Synonyms | indolethylamine N-methyltransferase, TEMT, Thioether S-methyltransferase |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Inmt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- thioether S-methyltransferase
- methyltransferase
- amine N-methyltransferase
- enzyme
- protein binding
- AdoMet_MTases
- methyltransferase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Inmt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- amine metabolic process
- response to toxin
- methylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- N-methyltransferase activity
- protein binding
- amine N-methyltransferase activity
- thioether S-methyltransferase activity