Usp50

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in Ras protein signal transduction; endosome organization; and regulation of cell cycle G2/M phase transition. Predicted to act upstream of or within several processes, including nuclear speck organization; positive regulation of NLRP3 inflammasome complex assembly; and positive regulation of cytokine production. Predicted to be located in centrosome; cytoplasm; and nucleus. Predicted to be active in cytosol; midbody; and postsynaptic density. Orthologous to human USP50 (ubiquitin specific peptidase 50). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Usp50 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Usp50 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Usp50 gene, providing context for its role in the cell.