Ints4 Gene Summary [Rat]

Predicted to be involved in snRNA processing. Predicted to be located in nucleolus. Predicted to be part of integrator complex. Predicted to be active in nucleus. Orthologous to human INTS4 (integrator complex subunit 4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ints4
Official Name
integrator complex subunit 4 [Source:RGD Symbol;Acc:1305036]
Ensembl ID
ENSRNOG00000012552
Bio databases IDs NCBI: 308837 Ensembl: ENSRNOG00000012552
Aliases integrator complex subunit 4
Synonyms 2610034N24Rik, INT4, integrator complex subunit 4, MST093, RGD1305036
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ints4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding activity, bridging
  • protein binding
  • HEAT repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • prostate cancer
  • prostatic carcinoma
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • interchromatin granule cluster fractions
  • Cytoplasm
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ints4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • snRNA processing
  • regulation of transcription elongation from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleolus
  • integrator complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.