Cst5 Gene Summary [Rat]

Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including bone mineralization; calcium ion homeostasis; and endochondral bone morphogenesis. Predicted to act upstream of or within cell maturation and chondrocyte differentiation. Predicted to be located in cytosol and extracellular region. Predicted to be active in cytoplasm; extracellular space; and vesicle. Orthologous to human CST5 (cystatin D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cst5
Official Name
cystatin D [Source:RGD Symbol;Acc:1310978]
Ensembl ID
ENSRNOG00000005545
Bio databases IDs NCBI: 366219 Ensembl: ENSRNOG00000005545
Aliases cystatin D
Synonyms Cst10, cystatin D, DD72
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cst5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CY
  • cysteine protease inhibitor activity

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
  • transmembrane potential
  • differentiation
  • endochondral ossification by
  • maturation
  • calcification
  • mineralization
  • homeostasis
  • fragmentation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Extracellular Space
  • cytosol

Gene-Specific Assays for Results You Can Trust

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