Fbxo10 Gene Summary [Rat]

Predicted to be involved in regulation of apoptotic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Orthologous to human FBXO10 (F-box protein 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fbxo10
Official Name
F-box protein 10 [Source:RGD Symbol;Acc:1305465]
Ensembl ID
ENSRNOG00000012634
Bio databases IDs NCBI: 362511 Ensembl: ENSRNOG00000012634
Aliases F-box protein 10
Synonyms F-box protein 10, FBX10, Gm634, PRMT11
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fbxo10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • F-box domain
  • Right handed beta helix region
  • F-box domain superfamily
  • Periplasmic copper-binding protein (NosD)
  • F-box-like
  • Protein of unknown function (DUF1565)
  • parallel beta-helix repeat (two copies)
  • enzyme
  • protein binding
  • Domain present in carbohydrate binding proteins and sugar hydrolses

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • beta-estradiol
  • 20-hydroxyeicosatetraenoic acid
  • sotrastaurin
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fbxo10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • apoptotic process
  • regulation of apoptotic process
  • protein ubiquitination
  • ubiquitin-dependent protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • ubiquitin ligase complex
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • ubiquitin-protein ligase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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