Col19a1 Gene Summary [Rat]
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within skeletal muscle tissue development. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human COL19A1 (collagen type XIX alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Col19a1 |
| Official Name | collagen type XIX alpha 1 chain [Source:RGD Symbol;Acc:1308920] |
| Ensembl ID | ENSRNOG00000012759 |
| Bio databases IDs | |
| Aliases | collagen type XIX alpha 1 chain |
| Synonyms | COL9A1L, COLLAGEN type XIX, collagen, type XIX, alpha 1, collagen type XIX alpha 1 chain, collagen, type XIX, α 1, collagen type XIX α 1 chain, D6S228E |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Col19a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NC1 domain
- LamG
- Collagen triple helix repeat (20 copies)
Pathways
Biological processes and signaling networks where the Col19a1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- collagenase
- CAND1
disease
- diabetic foot ulcer disorder
- Dupuytren contracture
- cellulite of the buttocks
- seizures
- neuroticism
- Peyronie disease
- diabetic nephropathy
- weight loss
- attention deficit hyperactivity disorder
- dysphagia
role in cell
- assembly
- number
- organization
- assembly in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- endoplasmic reticulum lumen
- basement membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Col19a1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- skeletal system development
- skeletal muscle tissue development
- extracellular matrix organization
- cell differentiation
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- extracellular space
- collagen
- extracellular matrix
- extracellular region
Molecular Function
What the gene product does at the molecular level
- extracellular matrix structural constituent conferring tensile strength
- protein binding, bridging
- extracellular matrix structural constituent