Efr3b Gene Summary [Rat]

Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to act upstream of or within social behavior and transmission of nerve impulse. Predicted to be located in actin cytoskeleton and cytosol. Predicted to be active in plasma membrane. Orthologous to human EFR3B (EFR3 homolog B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Efr3b
Official Name
EFR3 homolog B [Source:RGD Symbol;Acc:1310845]
Ensembl ID
ENSRNOG00000012950
Bio databases IDs NCBI: 313928 Ensembl: ENSRNOG00000012950
Aliases EFR3 homolog B
Synonyms AI852640, C030014M07Rik, EFR3 homolog B, KIAA0953, mKIAA0953, RGD1310845
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Efr3b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • insulin-dependent diabetes mellitus
  • breast carcinoma
  • atopic dermatitis
regulated by
regulates
  • phosphatidylinositol
role in cell
  • transmission

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • actin cytoskeleton
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Efr3b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phosphatidylinositol phosphorylation
  • protein localization in plasma membrane

Cellular Component

Where in the cell the gene product is active
  • actin cytoskeleton
  • cytosol
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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