Ddx31 Gene Summary [Rat]

Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in Golgi apparatus and nucleolus. Predicted to be active in nucleus. Orthologous to human DDX31 (DEAD-box helicase 31). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ddx31
Official Name
DEAD-box helicase 31 [Source:RGD Symbol;Acc:1304895]
Ensembl ID
ENSRNOG00000013040
Bio databases IDs NCBI: 311835 Ensembl: ENSRNOG00000013040
Aliases DEAD-box helicase 31
Synonyms 5830444G11, 5830444G11Rik, DEAD-box helicase 31, DEAD/H box helicase 31, Gm997, PPP1R25
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ddx31 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4217)
  • helicase superfamily c-terminal domain
  • DEAD/DEAH box helicase
  • Type III restriction enzyme, res subunit
  • N-terminal helicase domain of the DEAD-box helicase superfamily
  • protein binding
  • DEAD-like helicases superfamily
  • Helicase conserved C-terminal domain
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Burkitt lymphoma
  • liver cancer
  • colon cancer
  • B-cell non-Hodgkin disease
  • mature B-cell neoplasia
  • lung cancer
regulates
role in cell
  • processing in
  • biogenesis
  • interaction in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • intracellular membrane-bounded organelle
  • Golgi Apparatus
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ddx31 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosome biogenesis

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • intracellular membrane-bounded organelle
  • Golgi apparatus
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding
  • RNA binding
  • protein binding
  • RNA helicase activity

Gene-Specific Assays for Results You Can Trust

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