Ppp4r1 Gene Summary [Rat]

Predicted to enable protein phosphatase regulator activity. Predicted to be active in cytoplasm. Orthologous to human PPP4R1 (protein phosphatase 4 regulatory subunit 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ppp4r1
Official Name
protein phosphatase 4, regulatory subunit 1 [Source:RGD Symbol;Acc:619798]
Ensembl ID
ENSRNOG00000013733
Bio databases IDs NCBI: 140943 Ensembl: ENSRNOG00000013733
Aliases protein phosphatase 4, regulatory subunit 1
Synonyms 3110001J10Rik, MEG1, PP4R1, PP4(Rmeg), protein phosphatase 4 regulatory subunit 1, protein phosphatase 4, regulatory subunit 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppp4r1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • HEAT repeat
  • protein phosphatase
  • phosphatase
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • NFkB (complex)
  • IKKA/B
role in cell
  • survival

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ppp4r1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • protein dephosphorylation
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • protein phosphatase 4 complex

Molecular Function

What the gene product does at the molecular level
  • phosphoprotein phosphatase activity
  • protein binding
  • protein phosphatase regulator activity

Gene-Specific Assays for Results You Can Trust

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